GalNAc-T17 is a 601 amino acid single-pass type II membrane protein that is a member of the glycosyltransferase 2 family and GalNAc-T subfamily. Localized to the Golgi apparatus and contains a ricin B-type lectin domain, GalNAc-T17 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GalNAc-T17 contains two conserved domains, an N-terminal domain (domain A, also called GT1 motif), which is likely involved in manganese coordination and substrate binding and a C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-T17 exists as two alternatively spliced isoforms and utilizes manganese and calcium as cofactors.

EC 2.4.1.41;
GalNAc transferase 17;
GalNAc-T17;
GALNACT20;
GALNTL6;
GaNTase 17;
GLTL6_HUMAN;
MGC44629;
OTTHUMP00000219021;
OTTHUMP00000219023;
Polypeptide GalNAc transferase 17;
Polypeptide N-acetylgalactosaminyltransferase-like 6;
polypeptide N-acetylgalactosaminyltransferase-like 6 UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 20;
pp-GaNTase 17;
Protein-UDP acetylgalactosaminyltransferase 17;
Putative polypeptide N-acetylgalactosaminyltransferase 17;
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17;
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like.

Rat,Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Sheep

WB

WB 1:500-2000

70kD

442117

Q49A17

https://www.uniprot.org/uniprotkb/Q49A17

Golgi apparatus membrane.

KLH conjugated synthetic peptide derived from human GALNTL6

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.