NDFIP2 is a 336 amino acid protein that localizes to the membrane of both the endosome and the golgi apparatus. Expressed in kidney, heart, brain, lung, liver, placenta and skeletal muscle, Ndfip2 interacts with NEDD4 and NEDD4-L and is thought to be involved in endocytosis and in the NFⅹB and MAPK signaling pathways. Additionally, Ndfip2 may function as an adaptor protein that may recruit NEDD4 ubiquitin-protein ligases to protein trafficking machinery in the golgi. Ndfip2 is activated by T cells and may be ubiquitinated by NEDD4 or NEDD4-L, an event that does not affect Ndfip2 function. The gene encoding Ndfip2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.

Ndfip2;
NEDD4 family interacting protein 2;
NEDD4 family-interacting protein 2;
NEDD4 WW domain binding protein 5A;
NEDD4 WW domain-binding protein 5A;
NFIP2_HUMAN;
Putative MAPK activating protein PM04/PM05/PM06/PM07;
Putative MAPK-activating protein PM04/PM05/PM06/PM07;
Putative NF kappa B activating protein 413;
Putative NF-kappa-B-activating protein 413.

Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep

WB

WB 1:500-2000

36kD

54602

Q9NV92

https://www.uniprot.org/uniprotkb/Q9NV92

Endosome membrane. Golgi apparatus membrane. Endosome > multivesicular body membrane.

Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.

KLH conjugated synthetic peptide derived from human NDFIP2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.