Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.

3 keto acyl CoA synthase ELOVL1;
3-keto acyl-CoA synthase ELOVL1;
CGI 88;
Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1;
Elongation of very long chain fatty acids like 1;
Elongation of very long chain fatty acids protein 1;
ELOV1_HUMAN;
ELOVL 1;
ELOVL FA elongase 1;
ELOVL fatty acid elongase 1;
ELOVL1;
Ssc1;
very long chain 3 oxoacyl CoA synthase 1;
Very-long-chain 3-oxoacyl-CoA synthase 1.

Rat,Human,Mouse,Dog

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

33kD

64834

Q9BW60

https://www.uniprot.org/uniprotkb/Q9BW60

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Ubiquitous.

KLH conjugated synthetic peptide derived from human ELOVL1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.