Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]
SMC3 (phospho S1083); p-SMC3 (phospho S1083);
CDLS2;
DKFZp686L19178;
DXhXs423e;
DXS423E;
KIAA0178;
MGC138332;
OTTHUMP00000061876;
RP6 29D12.1;
SB1.8;
Segregation of mitotic chromosomes 1;
Segregation of mitotic chromosomes like 1;
SMC 1;
SMC protein 1B;
SMC-1-beta;
SMC-1B;
SMC1;
SMC1A;
SMC1alpha;
SMC1alpha protein;
SMC1B;
SMC1B_HUMAN;
SMC1BETA;
SMC1beta protein;
SMC1L1;
SMC1L2;
SMCB;
Structural maintenance of chromosome 1 like 1 protein;
Structural maintenance of chromosome 1 like 2 protein;
Structural maintenance of chromosomes 1A;
Structural maintenance of chromosomes 1B;
Structural maintenance of chromosomes protein 1B.
Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep
WB
WB 1:500-2000
141kD
9126
Q9UQE7
Nucleus. Chromosome. Chromosome > centromere. Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation.
KLH conjugated synthesised phosphopeptide derived from human SMC3 around the phosphorylation site of Ser1083
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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