Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.
ABC20;
ABCB1;
ATP binding cassette, sub family B (MDR/TAP), member 1;
ATP-binding cassette sub-family B member 1;
CD243;
CLCS;
Colchicin sensitivity;
Doxorubicin resistance;
GP170;
MDR1;
MDR1_HUMAN;
Multidrug resistance 1;
Multidrug resistance protein 1;
P glycoprotein 1;
P gp;
P-glycoprotein 1;
PGY1.
Human,Mouse,Rat
WB,IF,ICC,FC
WB 1:500-2000IF 1:100-1:400ICC 1:100-1:400FC 1:100
141kD
5243
P08183
Cell membrane; Multi-pass membrane protein.
Expressed in liver, kidney, small intestine and brain.
KLH conjugated synthetic peptide derived from human MDR1
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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