This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq, Jul 2008]

Beta-1,4-Galactosyltransferase 6;
UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 6;
UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 6;
UDP-Gal:Glucosylceramide Beta-1,4-Galactosyltransferase;
UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 6;
Beta-1,4-GalTase 6;
Beta4Gal-T6;
B4Gal-T6;
Beta4GalT-VI;
B4GT6_HUMAN;

Mouse,Rat,Human,Dog,Pig,Cow,Horse,Rabbit,Sheep

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

45kD

9331

Q9UBX8

https://www.uniprot.org/uniprotkb/Q9UBX8

Golgi apparatus

High expression in brain and adrenal gland, lower in liver, lung, colon and peripheral white blood cells.

KLH conjugated synthetic peptide derived from human B4GALT6

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.