Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
NFκB, a pleiotropic transcription factor, is present in almost all cell types and is involved in many biological processes including inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFκB is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFκB1/p105, NFκB1/p50, REL and NFκB2/p52. This complex is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NKAP (NF-κ-B-activating protein) is a 415 amino acid nuclear protein that regulates TNF and IL1-induced NFκB activation. As component of a DNA-binding complex, NKAP also functions as a transcriptional repressor that acts on NOTCH target genes. Loss of NKAP blocks the development of αβT- cells, suggesting that it is required for their maturation through repression of NOTCH genes.
NF-kappa-B-activating protein; Nkap; NKAP_HUMAN; Nuclear NF kappaB activating protein; Nuclear NF kappa B activating protein; NFkB activating protein.
Mouse,Human,Rat,Dog,Horse,Rabbit,Sheep
IHC,IF,ICC
IHC 1:100-500IF 1:100-500ICC 1:100-1:400
47kD
79576
Q8N5F7
Nucleus.
KLH conjugated synthetic peptide derived from human NKAP
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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