The pleiotropic IL3 (Interleukin 3) is a 15kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.

Colony stimulating factor multiple;
Hematopoietic growth factor;
IL 3;
IL3;
IL3_HUMAN;
IL3_MOUSE;
Interleukin 3 (colony stimulating factor, multiple);
Interleukin 3;
Interleukin-3;
Mast cell growth factor;
MCGF;
MGC79398;
MGC79399;
Multi CSF;
Multilineage colony stimulating factor;
Multipotential colony stimulating factor;
Multipotential colony-stimulating factor;
OTTHUMP00000065963;
P cell stimulating factor;
P-cell-stimulating factor

Mouse,Rat

WB,IHC,IF,ICC

WB 1:500-2000
IHC 1:100-500
IF 1:100-1:400
ICC 1:100-1:400

16kD

3562

P08700

https://www.uniprot.org/uniprotkb/P08700

Secreted.

Activated T-cells, mast cells, natural killer cells.

KLH conjugated synthetic peptide derived from mouse IL-3

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.