The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

2A5A_HUMAN;
B56A;
MGC131915;
PP2A B subunit B' alpha isoform;
PP2A B subunit B56 alpha isoform;
PP2A B subunit isoform B''-alpha;
PP2A B subunit isoform B56-alpha;
PP2A B subunit isoform PR61-alpha;
PP2A B subunit isoform R5-alpha;
PP2A B subunit PR61 alpha isoform;
PP2A B subunit R5 alpha isoform;
PPP2R5A;
PR61A;
PR61alpha;
Protein phosphatase 2 regulatory subunit B (B56) alpha isoform;
Protein phosphatase 2 regulatory subunit B alpha isoform;
Protein phosphatase 2 regulatory subunit B' alpha;
Serine/threonine protein phosphatase 2A 56kDa regulatory subunit alpha isoform;
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform.

Mouse,Human,Rat,Pig,Cow,Horse,Rabbit

WB

WB 1:500-2000

56kD

5525

Q15172

https://www.uniprot.org/uniprotkb/Q15172

Cytoplasm. Nucleus. Chromosome > centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase.

Widely expressed with the highest expression in heart and skeletal muscle.

KLH conjugated synthetic peptide derived from human PPP2R5A

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.