13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Members of the Leiomodin protein family are closely related to the tropomodulin family of actin filament pointed end-capping proteins. Leiomodins are actin-binding proteins that act as strong filament nucleators in muscle cells. Leiomodin 1 is highly expressed in a variety of tissues that contain smooth muscle, therefore it is also known as smooth muscle Leiomodin, or SM-Lmod. Also designated C-Lmod, Leiomodin 3 is found in several types of fetal tissue and is involved in tropomyosin binding. Leiomodin 2, also known as C-LMOD or LMOD2, is a 547 amino acid protein that is specifically expressed in heart and skeletal muscles. Leiomodin 2 binds to tropomyosin and may block the elongation and depolymerization of actin filaments at their pointed end. Leiomodin 2 is encoded by a gene that is located near the hypertrophic cardiomyopathy locus CMH6 on chromosome 7, suggesting that Leiomodin 2 may be involved in that disease process. Leiomodin 2 is expressed as three alternatively spliced variants.
C-LMOD;
Cardiac leiomodin;
Leiomodin 2 (cardiac);
Leiomodin-2;
LMOD2;
LMOD2_HUMAN.
Mouse,Human,Rat,Pig,Cow,Horse,Sheep
WB
WB 1:500-2000
62kD
442721
Q6P5Q4
Specifically expressed in heart and skeletal muscles. Not expressed in other tissues.
KLH conjugated synthetic peptide derived from human LMOD2
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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