PC21664

货号 规格 价格(¥)
PC21664S 50ul
PC21664M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Notch 2 Rabbit pAb

Datasheet

Background

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

Alternative Names

Neurogenic locus notch homolog protein 2; activated Notch 2; Notch2; hN2; Notch 2 extracellular truncation; Notch 2 intracellular domain; AGS2; hN2; Motch B; N2 antibody neurogenic locus notch homolog protein 2; NOTC2_HUMAN; Notch 2; Notch Drosophila homolog 2; Notch homolog 2; Notch homolog 2 Drosophila.

Reactivity

Mouse,Human,Rat,Dog

Application

WB

Recommended Dilution

WB 1:500-2000

Application Image

Mol Weight

262kD

Gene ID

4853

UniProt

Q04721

Uniprot link

Subcellular location

Cell membrane; Single-pass type I membrane protein. Notch 2 intracellular domain: Nucleus.

Specificity

Expressed in the brain, heart, kidney, lung, skeletal muscle and liver. Ubiquitously expressed in the embryo.

Immunogen

KLH conjugated synthetic peptide derived from human Notch 2

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

艾比玛特医药科技(上海)有限公司
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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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