Dcun1D3 is a 304 amino acid protein that contains one Dcun1 domain. The Dcun1 domain is an approximately 190 residue module that is thought to have the features of a basic helix-loop-helix leucine zipper domain, a domain commonly found in transcription factors. It has been suggested that Dcun1D3 may be involved in cell cycle progression and cell growth. The gene that encodes Dcun1D3 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Chromosome 16 houses the CREBBP gene that encodes a critical CREB binding protein that is responsible for the Rubinstein-Taybi syndrome, a rare disorder characterized by mental retardation and predisposition to tumor growth and white blood cell neoplasias.

44M2.4;
DCN1 defective in cullin neddylation 1 domain containing 3 (S. cerevisiae);
DCN1 defective in cullin neddylation 1 domain containing 3;
DCN1 like protein 3;
DCN1-like protein 3;
DCNL3_HUMAN;
DCUN1 domain containing protein 3;
DCUN1 domain-containing protein 3;
dcun1d3;
Defective in cullin neddylation protein 1 like protein 3;
Defective in cullin neddylation protein 1-like protein 3;
DKFZp686O0290;
FLJ41725;
MGC48972.

Human,Mouse,Rat

WB

WB 1:500-2000

34kD

123879

Q8IWE4

https://www.uniprot.org/uniprotkb/Q8IWE4

Contains 1 DCUN1 domain.

KLH conjugated synthetic peptide derived from human DCUN1D3

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.