Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes.

Dengue Virus 2 type NS1; DENV2; Dengue virus type 2 (strain China/D2-04); Dengue virus 2; DENV-2; Dengue virus type 2 (strain D2-04); Dengue virus type 2 China/D2-04; Dengue virus 2 China/D2-04; POLG_DEN2D; Genome polyprotein; DEN2;

Dengue Virus 2

WB,IHC,IF,ICC,ELISA

WB 1:500-2000
IHC 1:50-1:200
IF 1:100-1:400
ICC 1:100-1:400
ELISA 1:5000-10000

40kD

P30026

https://www.uniprot.org/uniprotkb/P30026

Capsid protein C: Virion (Potential).

Peptide pr: Secreted.

Small envelope protein M: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein.

Envelope protein E: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein.

Non-structural protein 1: Secreted. Host endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.

Non-structural protein 2A-alpha: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential).

Non-structural protein 2A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential).

Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.

Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Remains non-covalently associated to NS3 protease.

Non-structural protein 4A: Host endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Located in RE-associated vesicles hosting the replication complex.

Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein.

RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus. Note=Located in RE-associated vesicles hosting the replication complex.

KLH conjugated synthetic peptide derived from human DENV-2 NS1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.