The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD12 (potassium channel tetramerisation domain containing 12), also known as PFET1 or PFETIN, is a 325 amino acid protein that is expressed in fetal organs, with highest levels in the cochlea and brain and extremely low levels in adult organs, such as brain and lung. KCTD12 is considered a prognostic biomarker of gastrointestinal stromal tumors.

C13orf2; BTB/POZ domain-containing protein KCTD12; C13orf2; KCD12_HUMAN; KCTD12; KIAA1778; PFET1; Pfetin; potassium channel tetramerisation domain containing 12 USA; Predominantly fetal expressed T1 domain.

Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep

IHC,IF,ICC,ELISA

IHC 1:50-1:200
IF 1:100-500
ICC 1:100-1:400
ELISA 1:5000-10000

36kD

115207

Q96CX2

https://www.uniprot.org/uniprotkb/Q96CX2

Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.

Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.

KLH conjugated synthetic peptide derived from human KCTD12

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.