The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq].

MRP 14; MRP-14; MRP 8; MRP8; MRP-8; NIF; P14; P8; Protein S100 A8; Protein S100 A9; S100 A8; S100 A9; S100 calcium binding protein A8; S100 calcium binding protein A9; S100A8; S100A9; Urinary stone protein band A; 60B8AG; CAGA; CAGB; Calgranulin A; Calgranulin B; Calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; CP 10; CP10; Cystic fibrosis antigen; L1AG; Leukocyte L1 complex heavy chain; Leukocyte L1 complex light chain; LIAG; MA387; MAC387; MIF; MRP8 + MRP14; Migration inhibitory factor related protein 14; Migration inhibitory factor related protein 8.

Human,Mouse,Dog,Cow,Horse

WB

WB 1:500-2000

10kD

6279

P05109

https://www.uniprot.org/uniprotkb/P05109

Secreted. Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein.

Expressed by macrophages in chronic inflammations. Also expressed in epithelial cells constitutively or induced during dermatoses.

KLH conjugated synthetic peptide derived from human S100A8+S100A9

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.