Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).[supplied by OMIM, Mar 2008]

General transcription factor IIA;
General transcription factor IIA subunit 2;
General transcription factor IIA, 2 (12kD subunit);
General transcription factor IIA, 2, 12kDa;
gtf2a2;
HsT18745;
T2AG_HUMAN;
TF2A2;
TFIIA 12;
TFIIA;
TFIIA gamma;
TFIIA p12 subunit;
TFIIA-12;
TFIIA-gamma;
TFIIA12;
TFIIAS;
Transcription initiation factor IIA gamma chain;
Transcription initiation factor IIA subunit 2.

Mouse,Human,Rat,Horse

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

12kD

2958

P52657

https://www.uniprot.org/uniprotkb/P52657

Nucleus.

KLH conjugated synthetic peptide derived from human GTF2A2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.