Transcription initiation factor IIF subunit beta;
In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. TFIIF, a heteromer composed of a small (RAP 30) and a large (RAP 74) subunit, is required for RNA polymerase II to assemble into a preinitiation complex formed by promotor DNA and the general factors TFIID, IIA and IIB. In addition, TFIIF stimulates transcription elongation by RNA polymerase II.

ATP dependent helicase GTF2F2;
ATP-dependent helicase GTF2F2;
BTF4;
General transcription factor IIF 30 kDa subunit;
General transcription factor IIF polypeptide 2;
General transcription factor IIF subunit 2;
General transcription factor IIF, polypeptide 2, 30kDa;
Gtf2f2;
RAP30;
T2FB_HUMAN;
TF2F2;
TFIIF;
TFIIF beta;
TFIIF-beta.

Mouse,Human,Rat,Cow,Horse,Rabbit

WB

WB 1:500-2000

28kD

2963

P13984

https://www.uniprot.org/uniprotkb/P13984

Nucleus.

KLH conjugated synthetic peptide derived from human GTF2F2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.