This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

DKCB2;
FLJ20479;
H/ACA ribonucleoprotein complex subunit 2;
NHP2;
NHP2 like protein;
NHP2 ribonucleoprotein;
NHP2 ribonucleoprotein homolog (yeast) 1;
NHP2 ribonucleoprotein homolog;
NHP2, S. cerevisiae, homolog of;
NHP2_HUMAN;
NHP2P;
NOLA2;
Nucleolar protein family A member 2 (H/ACA small nucleolar RNPs);
Nucleolar protein family A member 2;
snoRNP protein NHP2.

Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

17kD

55651

Q9NX24

https://www.uniprot.org/uniprotkb/Q9NX24

Nucleus; nucleolus. Nucleus; Cajal body. Also localized to Cajal bodies.

Expressed in brain, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus. Also expressed at lower levels in the liver.

KLH conjugated synthetic peptide derived from human NHP2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.