Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.

Interferon induced GTP binding protein Mx2;
Interferon regulated resistance GTP binding protein MXB;
Interferon-induced GTP-binding protein Mx2;
Interferon-regulated resistance GTP-binding protein MxB;
MX 2;
MX dynamin like GTPase 2;
Mx2;
MX2_HUMAN;
MXB;
Myxovirus (influenza virus) resistance 2;
Myxovirus resistance 2;
Myxovirus resistance protein 2;
p78 related protein;
p78-related protein;
Second interferon induced protein p78.

Human

IHC,IF,ICC

IHC 1:100-500
IF 1:25
ICC 1:100-1:400

79kD

4600

P20591

https://www.uniprot.org/uniprotkb/P20591

Cytoplasm.

KLH conjugated synthetic peptide derived from human MX2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.