NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]

CLR19.6;
FLJ26273;
NACHT leucine rich repeat and PYD containing 11;
NACHT LRR and PYD domains containing protein 11;
NACHT, LRR and PYD domains-containing protein 11;
NAL11_HUMAN;
NALP11;
NLR family pyrin domain containing 11;
NLRP11;
NOD17;
Nucleotide binding oligomerization domain protein 17;
Nucleotide-binding oligomerization domain protein 17;
Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11;
PAAD and NACHT containing protein 10B;
PAAD and NACHT domain containing protein 10;
PAAD-and NACHT domain-containing protein 10;
PAN10;
PYPAF6;
PYPAF7;
PYRIN containing APAF1 like protein 6;
PYRIN-containing APAF1-like protein 6.

Human

WB

WB 1:500-2000

118kD

204801

P59045

https://www.uniprot.org/uniprotkb/P59045

KLH conjugated synthetic peptide derived from human NLRP11

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.