The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

KAT5 / Tip60 (phospho S90); p-KAT5 / Tip60 (phospho S90);
60 kDa Tat interactive protein;
60 kDa Tat-interactive protein;
cPLA(2) interacting protein;
cPLA(2)-interacting protein;
cPLA2;
cPLA2 interacting protein;
ESA1;
Histone acetyltransferase HTATIP;
Histone acetyltransferase KAT5;
HIV 1 Tat interactive protein;
HIV 1 Tat interactive protein, 60kDa;
HIV-1 Tat interactive protein;
HTATIP;
HTATIP1;
K(lysine) acetyltransferase 5;
K-acetyltransferase 5;
KAT5;
KAT5_HUMAN;
Lysine acetyltransferase 5;
PLIP;
Tat interacting protein, 60kDa;
TIP;
Tip60.

Mouse,Human,Rat,Pig,Cow,Horse,Rabbit,Sheep

WB

WB 1:500-2000

59kD

10524

Q92993

https://www.uniprot.org/uniprotkb/Q92993

Nucleus > nucleolus. Cytoplasm > perinuclear region. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region and UV irradiation induces translocation into punctuate subnuclear structures named nuclear bodies.

KLH conjugated synthesised phosphopeptide derived from human KAT5 around the phosphorylation site of Ser90

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.