SCGF is a cytokine for primitive hematopoietic progenitor cells and exhibits species-specific activity. It is predominantly expressed in proliferating chondrocytes, bone marrow cells, the periosteum and the perichondrium of skeletal tissues. SCGF contains an N-terminal Arg-Gly-Asp triplet (RGD triplet), leucine zipper domains, a C-terminal C-type lectin domain and numerous potential glycosylation sites. It has burst-promoting activity and granulocyte/macrophage colony-promoting activity in vitro. SCGF is directly correlated to granulocyte recovery following stem cell transplantation and thus can be an indicator of hematopoietic recovery following stem cell transplantation.

SCGF beta;
C type lectin domain family 11 member A;
C type lectin superfamily member 3;
C-type lectin domain family 11 member A;
C-type lectin superfamily member 3;
CLC11_HUMAN;
CLEC11A;
CLECSF3;
LSLCL;
Lymphocyte secreted C type lectin;
Lymphocyte secreted C-type lectin;
lymphocyte secreted long form of C type lectin;
p47;
Stem cell growth factor;
stem cell growth factor lymphocyte secreted C type lectin.

Human

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

34kD

6320

Q9Y240

https://www.uniprot.org/uniprotkb/Q9Y240

Cytoplasm. Secreted.

Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.

KLH conjugated synthetic peptide derived from human SCGF

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.