This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011]

cytoplasmic RNA-interacting protein;
dJ3J17.2;
Glycine and tyrosine rich RNA binding protein;
Glycine- and tyrosine-rich RNA-binding protein;
GRY RBP;
GRY-RBP;
Heterogeneous nuclear ribonucleoprotein Q;
hnRNP Q;
HNRPQ 1;
HNRPQ;
HNRPQ_HUMAN;
HNRPQ1;
NS1 associated protein 1;
NS1-associated protein 1;
NSAP 1;
NSAP1;
pp68;
RP1 3J17.2;
Synaptotagmin binding cytoplasmic RNA interacting protein;
Synaptotagmin-binding;
SYNCRIP.

Mouse,Rat,Human,Cow,Horse

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

69kD

10492

O60506

https://www.uniprot.org/uniprotkb/O60506

Nucleus > nucleoplasm. Expressed predominantly in the nucleoplasm and Cytoplasm. Microsome. Endoplasmic reticulum. Nucleus. The tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity). Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Ubiquitously expressed. Detected in heart, brain, pancreas, placenta, spleen, lung, liver, skeletal muscle, kidney, thymus, prostate, uterus, small intestine, colon, peripheral blood and testis.

KLH conjugated synthetic peptide derived from human hnRNP Q

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.