DHDPSL is a 327 amino acid mitochondrial protein that catalyzes the last step in the hydroxyproline metabolic pathway. Existing as two alternatively spliced isoforms, DHDPSL is expressed in kidney and liver and is inhibited by divalent cations. Defects in the gene that encode DHDPSL are the cause of primary hyperoxalurea type III (HP3), a disorder of calcium oxalate nephrolithiasis. Patients with HP3 excrete urine with elevated levels of oxalate and L-glycerate. The DHDPSL gene maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria

4 hydroxy 2 oxoglutarate aldolase 1;
C10orf65;
DHDPS like protein;
DHDPS2;
DHDPSL;
Dihydrodipicolinate synthase like;
Dihydrodipicolinate synthase like, mitochondrial;
Dihydrodipicolinate synthetase homolog 2;
FLJ37472;
HOGA1;
HOGA1_HUMAN;
HP3;
mitochondrial;
N acetylneuraminate pyruvate lyase 2 (putative);
NPL2;
Probable 2 keto 4 hydroxyglutarate aldolase;
Probable 4 hydroxy 2 oxoglutarate aldolase mitochondrial;
Probable 4-hydroxy-2-oxoglutarate aldolase;
Probable KHG aldolase;
Protein 569272.

Mouse,Human

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

32kD

112817

Q86XE5

https://www.uniprot.org/uniprotkb/Q86XE5

KLH conjugated synthetic peptide derived from human HOGA1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.