Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Function: Meiosis-specific component of some cohesin complex. Probably required during early meiosis for separation of sister chromatids and homologous chromosomes. Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I. May be involved in synapsis initiation and crossover recombination between homologous chromosomes. Subunit structure: Component of some meiotic cohesin complex composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domain, RAD21L which link them, and STAG3. Sequence similarities Belongs to the rad21 family.
dJ545L17.2;
Double-strand-break repair protein rad21-like protein 1;
RAD21L;
RP11-314N13.7.
Rat,Human,Mouse,Horse
IHC,IF,ICC
IHC 1:100-500IF 1:100-500ICC 1:100-1:400
63kD
642636
Q9H4I0
Nucleus. Chromosome. Note: In meiotic chromosomes, localized along axial elements in early meiosis: detectable on the axial elements in leptotene, and stays on the axial/lateral elements until mid pachytene. It then disappears and is replaced with RAD21. Compared to REC8, has mutually exclusive loading sites on the chromosomes: REC8 and RAD21L form distinct cohesin-enriched domains along the axial elements.
Specifically expressed in male and female gonads (at protein level).
KLH conjugated synthetic peptide derived from human RAD21L1
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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