Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009]

CK-72;
Cytokeratin-72;
K2C72_HUMAN;
K6irs;
K6IRS2;
K72;
KB35;
Keratin 6 inner root sheath 2;
keratin protein K6irs;
Keratin type II cytoskeletal 72;
Keratin-72;
KRT6;
KRT6IRS2;
Krt72;
Type II inner root sheath-specific keratin-K6irs2;
Type-II keratin Kb35.

Mouse,Human,Rat,Rabbit

WB

WB 1:500-2000

56kD

140807

Q14CN4

https://www.uniprot.org/uniprotkb/Q14CN4

Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level).

KLH conjugated synthetic peptide derived from human KRT72

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.