CLP46 is a KTEL motif-containing protein that belongs to the CAP10 family. The KTEL motif at the C-terminus of CLP46 is an endoplasmic reticulum (ER) retention signal which localizes the CLP46 protein to the lumen of the ER. CLP46 is thought to promote cell proliferation and is also believed to be involved with hepatic functions. The Drosophila protein rumi, a CAP10 protein and likely similar in function to CLP46, uses glucosylation to act as a Notch signaling regulator. Expressed in varying degrees in most adult tissue, CLP46 is especially abundant in the liver. CLP46 is not expressed in detectable levels in colon, thymus or small intestine. Human CLP46 shares 94% and 91% sequence similarity with its bovine and mouse homologs, respectively.

C3orf9;
CAP10 like 46 kDa protein;
CAP10 like protein, 46 kDa;
CLP46;
hCLP46;
KDELC family like 1;
KDELCL1;
KTEL (Lys Tyr Glu Leu) containing 1;
KTEL motif containing protein 1;
KTELC1;
MDS010;
MDSRP;
myelodysplastic syndromes relative protein;
POGLUT1;
protein O glucosyltransferase 1;
Rumi;
x 010 protein.

Mouse,Human,Rat,Dog,Cow,Horse,Rabbit,Sheep

WB

WB 1:500-2000

43kD

56983

Q8NBL1

https://www.uniprot.org/uniprotkb/Q8NBL1

Endoplasmic reticulum lumen.

Expressed in most adult tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine.

KLH conjugated synthetic peptide derived from human KTEL1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.