This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

Cirhin interaction protein;
CIRIP;
CRYBP1;
GAAP;
Gate keeper of apoptosis-activating protein;
HIV EP1;
HIV-EP1;
HIVEP 1;
Hivep1;
Human immunodeficiency virus type I enhancer binding protein 1;
Human immunodeficiency virus type I enhancer-binding protein 1;
Major histocompatibility complex binding protein 1;
Major histocompatibility complex-binding protein 1;
MBP 1;
MBP-1;
Positive regulatory domain II binding factor 1;
Positive regulatory domain II-binding factor 1;
PRDII BF1;
PRDII-BF1;
Schnurri 1;
ZAS1;
ZEP1_HUMAN;
Zinc finger protein 40;
ZNF40;
ZNF40A.

Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep

IHC,IF,ICC,ELISA

IHC 1:50-1:200
IF 1:100-500
ICC 1:100-1:400
ELISA 1:5000-10000

297kD

3096

P15822

https://www.uniprot.org/uniprotkb/P15822

Cytoplasm. Nucleus and Nucleus.

KLH conjugated synthetic peptide derived from human HIVEP1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.