PC16622

货号 规格 价格(¥)
PC16622S 50ul
PC16622M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-SPPL2C Rabbit pAb

Datasheet

Background

Intramembrane proteolysis is now widely recognized as an important physiological pathway required for reverse signaling and membrane protein degradation. Aspartyl intramembrane cleaving proteases of the GXGD-type play an important regulatory role in health and disease. Signal peptide peptidase (SPP) and SPP-like (SPPL) peptidases, such as SPPL2a, SPPL2b, IMP5, and SPPL3, belong to the family of GXGD aspartic proteases. The putative catalytic domains of SPP and SPPLs are embedded in membranes in an orientation predisposed to cleave type II oriented transmembrane proteins. IMP5 (intramembrane protease 5), also known as SPPL2c (signal peptide peptidase-like 2C), is a 690 amino acid multi-pass membrane protein that may act as an intramembrane protease. IMP5 also belongs to the peptidase A22B family and two isoforms are produced by alternative splicing events.

Alternative Names

IMP-5;
IMP5;
SPP2C_HUMAN;
Intramembrane protease 5;
Signal peptide peptidase-like 2C;
SPP-like 2C;

Reactivity

Human,Mouse,Rat

Application

IHC,IF,ICC,ELISA

Recommended Dilution

IHC 1:50-1:200
IF 1:100-500
ICC 1:100-1:400
ELISA 1:5000-10000

Application Image

Mol Weight

72kD

Gene ID

162540

UniProt

Q8IUH8

Uniprot link

Subcellular location

Membrane.

Specificity

Immunogen

KLH conjugated synthetic peptide derived from human SPPL2C

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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