Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside.

MCP-1/CCL2; C-C motif chemokine 2;
CCL 2;
CCL2;
CCL2_HUMAN;
Chemokine (C C motif) ligand 2;
Chemokine C C motif ligand 2;
Chemokine CC Motif Ligand 2;
GDCF 2;
GDCF 2 HC11;
GDCF-2;
GDCF2;
HC11;
HSMCR30;
HSMCR30;
JE;
MCAF;
MCP 1;
MCP-1;
MGC9434;
Monocyte chemoattractant protein 1;
Monocyte chemotactic and activating factor;
Monocyte chemotactic protein 1;
Monocyte secretory protein JE;
SCYA2;
Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je);
Small inducible cytokine A2;
Small inducible cytokine subfamily A (Cys Cys), member 2;
Small inducible cytokine subfamily A Cys Cys member 2;
Small-inducible cytokine A2;
SMC CF;
SMC-CF;
SMCCF.

Mouse,Rat,Human

WB,ELISA

WB 1:500-2000
ELISA 1:5000-1:20000

11kD

24770

P13500

https://www.uniprot.org/uniprotkb/P13500

Secreted.

KLH conjugated synthetic peptide derived from human MCP-1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.