Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated.

Tonsillar lymphocyte LD78 alpha protein; CCL 3; CCL3; Chemokine C C motif ligand 3; Chemokine CC Motif Ligand 3; G0/G1 switch regulatory protein 19 1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein antibody
L2G25B; LD78ALPHA; Macrophage inflammatory protein 1 alpha; MIP 1 alpha; MIP-1 Alpha; MIP 1A; MIP1A; PAT 464.1; SCYA 3; SCYA3; SIS alpha; SIS beta; Small inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; CCL3_HUMAN; CCL3_MOUSE;

Human,Mouse,Rat

ELISA

ELISA 1:5000-10000

7.9kD

6348

P10147

https://www.uniprot.org/uniprotkb/P10147

Secreted.

Expressed in lung, spleen, and pancreas.

KLH conjugated synthetic peptide derived from mouse CCL3

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.