This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]

MSL3;
AU018931;
DKFZp586J1822;
Drosophila MSL3 like 1;
Male specific lethal 3 (Drosophila) like 1;
Male specific lethal 3 homolog (Drosophila);
Male specific lethal 3 homolog 1 (Drosophila);
Male specific lethal 3 homolog 1;
Male specific lethal 3 homolog;
Male specific lethal 3 like 1 (Drosophila);
Male specific lethal 3 like 1;
Male specific lethal 3 protein like 1;
Male-specific lethal 3 homolog;
Male-specific lethal-3 homolog 1;
Male-specific lethal-3 protein-like 1;
MS3L1_HUMAN;
MSL3;
MSL3 like 1;
MSL3-like 1;
Msl31;
MSL3L1;
OTTHUMP00000022911;
OTTHUMP00000022912.

Human,Mouse,Dog,Pig,Cow,Horse,Sheep,GuineaPig

WB

WB 1:500-2000

60kD

10943

Q8N5Y2

https://www.uniprot.org/uniprotkb/Q8N5Y2

Nucleus

Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.

KLH conjugated synthetic peptide derived from human MSL3L1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.