This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]

CYTH3;
ARF nucleotide-binding site opener 3;
ARNO3;
ARNO3 protein;
CYH3_HUMAN;
Cyth3;
Cytohesin-3;
General receptor of phosphoinositides 1;
Grp1;
PH;
PH, SEC7 and coiled-coil domain-containing protein 3;
Protein ARNO3;
PSCD3;
SEC7 and coiled-coil domain-containing protein 3;
SEC7 homolog C;
Sec7-3;
Sec7c.

Mouse,Human,Rat,Cow,Horse,Rabbit,Sheep

WB

WB 1:500-2000

46kD

9265

O43739

https://www.uniprot.org/uniprotkb/O43739

Cell membrane.

Almost absent from liver, thymus and peripheral blood lymphocytes.

KLH conjugated synthetic peptide derived from human Cytohesin 3

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.