The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Neuronal calcium-binding protein;
amyloid beta (A4) precursor protein binding, family A, member 2 binding protein;
Amyloid beta A4 protein binding family A member 2 binding protein;
Amyloid beta A4 protein-binding family A member 2-binding protein;
APBA2BP;
dJ63M2.4;
dJ63M2.5;
EFCBP3;
N terminal EF hand calcium binding protein 3;
N-terminal EF-hand calcium-binding protein 3;
NECA3_HUMAN;
NECAB3;
NECAB3;
Nek2 interacting protein 1;
Nek2-interacting protein 1;
Neuronal calcium binding protein 3;
Neuronal calcium-binding protein 3;
NIP1;
STIP3;
Synaptotagmin interacting protein 2;
SYTIP2;
X11L binding protein 51;
X11L-binding protein 51;
XB51.

Mouse,Human,Rat,Cow,Sheep

WB

WB 1:500-2000

44kD

63941

Q96P71

https://www.uniprot.org/uniprotkb/Q96P71

Golgi apparatus.

Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas.

KLH conjugated synthetic peptide derived from human NECAB3

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.