HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008).

Core protein; Hepatitis C virus subtype 1b;
E1 protein;
E2 protein;
Envelope glycoprotein E2;
gp68;
gp70;
HCV E2;
NS1;
NS2 protein;
NS3 protease/helicase;
NS4A protein;
NS4B protein;
NS5A protein;
NS5B RNA dependent RNA polymerase;
P7 protein.

Hepatitis C Virus

ELISA

ELISA 1:5000-10000

40kD

Q14SZ0

https://www.uniprot.org/uniprotkb/Q14SZ0

Non-structural protein 5A: Host endoplasmic reticulum membrane; Peripheral membrane protein. Host cytoplasm, host perinuclear region. Host mitochondrion. Note=Host membrane insertion occurs after processing by the NS3 protease.

KLH conjugated synthetic peptide derived from human Hepatitis C Virus E2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.