PC41381

货号 规格 价格(¥)
PC41381S 50ul
PC41381M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-DDR2 Rabbit pAb

Datasheet

Background

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

Alternative Names

DDR 2; DDR 2; CD167b antigen; Cell migration inducing protein 20; Discoidin domain containing receptor 2; Discoidin domain receptor 2; Discoidin domain receptor family member 2v Hydroxyaryl protein kinase; MIG20a; Migration inducing gene 16 protein; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase receptor related 3v NTRKR 3; NTRKR3v Receptor protein tyrosine kinase TKTv Receptor related 3; TKTv TYRO 10; TYRO10; Tyrosine kinase receptor related to neurotrophic TRK; Tyrosine protein kinase TYRO 10; Tyrosine protein kinase TYRO10; Tyrosylprotein kinase; DDR2_HUMAN; Discoidin domain-containing receptor 2; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; CD167b.

Reactivity

Human

Application

WB,ELISA

Recommended Dilution

WB 1:500-2000
ELISA 1:5000-10000

Application Image

Mol Weight

92kD

Gene ID

4921

UniProt

Q16832

Uniprot link

Subcellular location

Cell membrane; Single-pass type I membrane protein.

Specificity

Detected in osteocytes, osteoblastic cells in subchondral bone, bone lining cells, tibia and cartilage. Detected at high levels in heart and lung, and at low levels in brain, placenta, liver, skeletal muscle, pancreas, and kidney.

Immunogen

Recombinant human DDR2 protein

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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