p52 S6 kinase, also known as RPS6KC1 (ribosomal protein S6 kinase, 52kDa, polypeptide 1) or RPK118, is a 1,066 amino acid member of the Ser/Thr kinase family that localizes to both the cytoplasm and the nucleus and contains one MIT domain, one PX domain and two protein kinase domains. Expressed at high levels in brain, placenta, heart, testis, kidney, liver and skeletal muscle, p52 S6 kinase catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.

p52 S6 kinase;
52 kDa ribosomal protein S6 kinase;
humS6PKh1;
KS6C1_HUMAN;
Ribosomal protein S6 kinase 52kD polypeptide 1;
Ribosomal protein S6 kinase 52kDa polypeptide 1;
Ribosomal protein S6 kinase delta 1;
Ribosomal protein S6 kinase delta-1;
Ribosomal S6 kinase like protein with two PSK domains 118 kDa protein;
Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein;
RPK 118;
RPK118;
RPS6KC1;
S6K-delta-1;
SPHK1 binding protein;
SPHK1-binding protein.

Mouse,Human,Rat,Pig,Cow,Horse,Sheep

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

119kD

26750

Q96S38

https://www.uniprot.org/uniprotkb/Q96S38

Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures.

Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.

KLH conjugated synthetic peptide derived from human RPS6KC1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.