PC17488

货号 规格 价格(¥)
PC17488S 50ul
PC17488M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-DC-SIGNR1/CD209b Rabbit pAb

Datasheet

Background

Antigen-presenting cells are localized in essentially every tissue, where they operate at the interface of innate and acquired immunity by capturing pathogens and presenting pathogen-derived peptides to T cells. Dendritic cells capture antigens or viruses in peripheral tissue and transport them to lymphoid organs, an event that induces cellular T cell responses. The mouse CD209 family of cell adhesion receptors consists of CD209a (also known as DC-SIGN), CD209b, CD209c, CD209d, CD209e, CD209f and CD209g, all of which function to mediate the endocytosis and subsequent degradation of pathogens within lysosomal compartments. There are two human CD209 proteins, designated DC-SIGN and DC-SIGNR, which function in a similar manner to the mouse proteins.

Alternative Names

SIGN Related 1;
CD209 antigen like protein B;
CD209b antigen;
DC SIGN related protein 1;
DC SIGNR1;
OtB7.

Reactivity

Mouse

Application

WB

Recommended Dilution

WB 1:500-2000

Application Image

Mol Weight

37kD

Gene ID

69165

UniProt

Q8CJ91

Uniprot link

Subcellular location

Membrane Single-pass type II membrane protein

Specificity

Expressed in skin, spleen and lung, probably in a subset of dendritic cells. Detected in spleen extrafollicular paracortical areas including the red pulp and marginal zones, and at lower levels, in the follicular area. Detected in skin suprabasal areas adjacent to the epidermis and in epidermal cell layer.

Immunogen

KLH conjugated synthetic peptide derived from mouse CD209b

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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