Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The synculein family consists of 3 highly conserved proteins of between 120 and 140 amino acids that share substantial sequence homology. Each has a series of loosely repeated motifs throughout the first 93 amino acids and an acid region toward the C terminal. The proteins are heat stable and relatively soluble. Three synucleins have been identified and termed alpha, beta and gamma synuclein and are located in the neuronal cytosol and enriched in presynaptic terminals,gamma synuclein is also expressed in many other non-neuronal tissues. Although the precise function of the synucleins are unknown a role in membrane plasticity has been suggested. The synucleins have been implicated in a number of diseases. It has been reported that in breast cancer increased expression of gamma synuclein correlates with disease progression.
BCSG1; gamma-Synuclein; Breast cancer specific gene 1 protein; Breast cancer specific protein 1; Breast cancer-specific gene 1 protein; Gamma synuclein; Persyn; PRSN; SNCG; SR; Synoretin; Synuclein gamma; SYUG_HUMAN.
Rat,Human,Mouse,Dog
IHC,IF,ICC
IHC 1:100-500IF 1:100-500ICC 1:100-1:400
13.5kD
6623
O76070
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.
KLH conjugated synthetic peptide derived from human gamma Synuclein
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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