LBXCOR1 is a 965 amino acid protein belonging to the SKI family. Localizing to nucleus, LBXCOR1 is highly expressed in the central nervous system (CNS) as well as developing spinal cord and adult brain and testis. LBXCOR1 contains a CH1 domain which is required for transcriptional repression and also acts as a transcriptional co-repressor of LBX1. LBXCOR1 additionally interacts with SMAD1, SMAD2 and SMAD3, and inhibits BMP signaling. Existing as three alternatively spliced isoforms, the gene encoding LBXCOR1 maps to human chromosome 15q23. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and consists of about 3% of the human genome. Angelman and Prader-Willi syndromes, as well as Tay-Sachs disease and Marfan syndorme, are all associated with mutations to chromosome 15.

AV273001;
C230094B15Rik;
Corepressor for LBX1;
CORL1;
Functional smad suppressing element 15;
Functional Smad suppressing element on chromosome 15;
Functional Smad-suppressing element on chromosome 15;
Fussel-15;
FUSSEL15;
Ladybird homeobox corepressor 1;
Lbx1 corepressor 1;
LBXCOR1;
Lbxcor1 homolog;
SKI family transcriptional corepressor 1;
Skor1;
SKOR1_HUMAN;
Transcriptional corepressor CORL1.

Mouse,Rat,Human,Pig,Cow,Horse,Rabbit,Sheep

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

100kD

390598

P84550

https://www.uniprot.org/uniprotkb/P84550

Nucleus.

Present specifically in cerebellar Purkinje cells (at protein level).

KLH conjugated synthetic peptide derived from human SKOR1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.