This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]

Cadherln-related neuronal receptor2; Cadherin related neuronal receptor 2; CNR 2; CNR2; CNRN 2; CNRN2; CNRS 2; CNRS2; CRNR 2; CRNR2; KIAA0345 like 8; PCDH alpha6; PCDHA 6; PCDHA-6; PCDA6_HUMAN; PCDH-alpha-6; PCDHA6; Protocadherin alpha-6; Protocadherin alpha 6.

Rat,Human,Mouse,Cow,Horse

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

100kD

56142

Q9UN73

https://www.uniprot.org/uniprotkb/Q9UN73

Isoform 1: Cell membrane; Single-pass type I membrane protein.

Isoform 2: Secreted (Potential).

KLH conjugated synthetic peptide derived from human CNR-2

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.