ZDHHC13 is a 622 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and six ANK repeats. Expressed as multiple alternatively spliced isoforms, HIP14L functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and a protein-cyeteine to an S-palmitoyl protein and CoA and, via this catalytic activity, may be involved in the NFⅹB signaling pathway. The gene encoding HIP14L maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

DHHC 13;
DHHC-13;
FLJ10852;
FLJ10941;
HIP14 like;
HIP14 related protein;
HIP14-related protein;
HIP14L;
HIP3RP;
Huntingtin interacting protein 14 related protein;
Huntingtin interacting protein HIP3RP;
Huntingtin-interacting protein 14-related protein;
Huntingtin-interacting protein HIP3RP;
Hypothetical protein similar to ankyrin repeat containing priotein AKR1;
MGC64994;
Palmitoyltransferase ZDHHC13;
Probable palmitoyltransferase ZDHHC13;
Putative MAPK activating protein PM03;
Putative MAPK-activating protein PM03;
Putative NF kappa B activating protein 209;
Putative NF-kappa-B-activating protein 209;
ZDH13_HUMAN;
ZDHHC 13;
ZDHHC13;
Zinc finger DHHC domain containing 13;
Zinc finger DHHC domain-containing protein 13.

Human,Rat,Mouse

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

71kD

54503

Q8IUH4

https://www.uniprot.org/uniprotkb/Q8IUH4

Golgi apparatus membrane. Cytoplasmic vesicle membrane. Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles.

KLH conjugated synthetic peptide derived from human ZDHHC13/HIP14L

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.