SZT2 (seizure threshold 2 homolog (mouse)), also known as SZT2A or SZT2B, is a 3,432 amino acid peroxisomal protein that plays a role in resistance to oxidative stress. Predominantly expressed in the parietal and frontal cortex, as well as in dorsal root ganglia of the brain, SZT2 is implicated in superoxide dismutase activity and the neuroprotection in peroxisomes. Existing as four alternatively spliced isoforms, SZT2 is thought to enhance epileptogenesis and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

KIAA0467;
Chromosome 1 open reading frame 84;
FLJ34502;
Hypothetical protein LOC23334;
Protein SZT2;
RP11-506B15.1;
Seizure threshold 2 homolog A;
Seizure threshold 2 protein homolog;
SZT2;
SZT2_HUMAN;
SZT2A;
Uncharacterized protein KIAA0467.

Rat,Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

377kD

23334

Q5T011

https://www.uniprot.org/uniprotkb/Q5T011

Peroxisome (By similarity).

Expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia.

KLH conjugated synthetic peptide derived from human C1orf84

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.