This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]

3-D-mannoside beta-1;
3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B;
4-N-acetylglucosaminyltransferase IVb;
Alpha 1 3 mannosyl glycoprotein beta 1 4 N acetylglucosaminyltransferase;
Alpha-1;
Aminyltransferase;
GlcNAc T IVb;
GlcNAc-T IVb;
GNT IV;
GNT IVB;
GnT-IVb;
GNTIV;
GNTIVB;
Mannosyl (alpha 1 3) glycoprotein beta 1 4 N acetylglucosaminyltransferase isozyme B;
MGAT 4B;
mgat4b;
MGT4B_HUMAN;
N acetylglucosaminyltransferase IVb;
N glycosyl oligosaccharide glycoprotein;
N glycosyl oligosaccharide glycoprotein N acetylglucosaminyltransferase IVb;
N-acetylglucosaminyltransferase IVb;
N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb;
UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IV;
UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IVb;
UDP-N-acetylglucosamine: alpha-1.

Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep

WB

WB 1:500-2000

60kD

11282

Q9UQ53

https://www.uniprot.org/uniprotkb/Q9UQ53

Golgi apparatus membrane.

Widely expressed. Strongly overexpressed in pancreatic cancer.

KLH conjugated synthetic peptide derived from human MGAT4B

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.