Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

E 70/85kD;
TAF 6;
TAF2E;
TAF6 RNA polymerase II TATA box binding protein (TBP) associated factor 80 kD;
TAF6 RNA polymerase II, TATA box binding protein associated factor,80kDa;
TAFII 70;
TAFII80;
TATA box binding protein (TBP) associated factor RNA polymerase II E 70/85kD;
TATA box binding protein (TBP) associated factor, RNA polymerase II,;
TBP associated factor 6;
Transcription initiation factor TFIID 70 kDa subunit;
Transcription initiation factor TFIID subunit 6.

Human,Mouse,Rat,Dog,Cow,Sheep

WB,IHC,IF,ICC,ELISA

WB 1:500-2000
IHC 1:50-1:200
IF 1:100-1:400
ICC 1:100-1:400
ELISA 1:5000-10000

73kD

6878

P49848

https://www.uniprot.org/uniprotkb/P49848

Nuclear.

KLH conjugated synthetic peptide derived from human TAF6

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.