MPZL1 is a 269 amino acid widely expressed single-pass type I membrane receptor belonging to the myelin P0 protein family and the immunoglobulin superfamily. MPZL2 (myelin protein zero-like 2), also known as EVA (epithelial V-like antigen) or EVA1, is a 215 amino acid single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain and two potential N-glycosylation sites in its extracellular domain, MPZL2 is expressed in thymus epithelium and is strongly down-regulated by thymocyte developmental progression. MPZL3 (myelin protein zero-like 3) is a 235 amino acid single-pass type I membrane protein that regulates homophilic cell-to-cell adhesion. A member of the myelin P0 protein family, MPZL3 contains one Ig-like V-type (immunoglobulin-like) domain and is expressed in brain, heart, liver and skin. g to the myelin P0 protein family and the immunoglobulin superfamily. Existing as four alternatively spliced isoforms, MPZL1 participates in signal transduction and cell migration.

immunoglobulin family transmembrane protein;
MPZL1;
MPZL1b; MPZL1_HUMAN;
myelin protein zero like 1;
myelin protein zero like protein 1 precursor;
myelin protein zero like protein MPZL1b;
OTTHUMP00000032519;
protein zero related;
PZR;
PZR1b;
PZRa;
PZRb.

Mouse,Human,Rat,Dog,Cow,Horse,Rabbit,Sheep

WB

WB 1:500-2000

26kD

9019

O95297

https://www.uniprot.org/uniprotkb/O95297

Membrane; single pass type I membrane protein (Potential)

Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hematopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progenitors. Isoform 3 appears to be the major isoform in CD34- promyelocytic and promonocytic cells. During differentiation in monocytic cells, the expression level of isoform 3 decreases and that of isoform 1 increases. Isoform 1 is prominent in stromal cells and, to a lesser extent, in umbilical vein endothelial cells and erythroid progenitors. Isoform 2 is expressed in a erythroid progenitor cell line.

KLH conjugated synthetic peptide derived from human MPZL

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.