This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

cAMP responsive element binding protein 3 like 4; JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP; CR3L4_HUMAN; Cyclic AMP-responsive element-binding protein 3-like protein 4; cAMP-responsive element-binding protein 3-like protein 4; Androgen-induced basic leucine zipper protein; Attaching to CRE-like 1; Cyclic AMP-responsive element-binding protein 4; CREB-4; cAMP-responsive element-binding protein 4; Transcript induced in spermiogenesis protein 40; Tisp40; Processed cyclic AMP-responsive element-binding protein 3-like protein 4.

Human,Rat

WB

WB 1:500-1000

21kD

78284

Q9D2A5

https://www.uniprot.org/uniprotkb/Q9D2A5

Nucleus. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus and Endoplasmic reticulum membrane. Golgi apparatus membrane. May also be located in Golgi apparatus.

According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines. Expressed in prostatic luminal epithelial cells (at protein level). Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia). According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus.

Recombinant human CREB3L4 between 1-300 amino acids.

Mouse

Monoclonal

IgG1

affinity purified by Protein G

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.