The multifunctional CaMKII beta, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CaMKII is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Autophosphorylation plays an important role in the regulation of the kinase activity. CaMKII is required for synaptic plasticity, as in Long Term Potentiation (LTP), a cellular model for learning and memory.

Calcium/calmodulin dependent protein kinase (CaM kinase) II beta;
Calcium/calmodulin dependent protein kinase II beta;
Calcium/calmodulin dependent protein kinase IIB;
Calcium/calmodulin dependent protein kinase type II beta chain;
calcium/calmodulin-dependent protein kinase II beta;
Calcium/calmodulin-dependent protein kinase type II subunit beta;
CAM 2;
CaM kinase II beta chain;
CaM kinase II beta subunit;
CaM kinase II subunit beta;
CaM-kinase II beta chain;
CAM2;
CAMK 2;
CAMK 2B;
CaMK II beta subunit;
CaMK II subunit beta;
CaMK-II subunit beta;
CAMK2;
Camk2b;
CAMKB;
CaMKII beta subunit;
CaMKIIB;
KCC2B_HUMAN;
MGC29528;
Proline rich calmodulin dependent protein kinase;
proline rich calmodulin-dependent protein kinase;

Human,Mouse,Rat

WB,IHC,IF,ICC

WB 1:500-2000
IHC 1:25
IF 1:100-1:400
ICC 1:100-1:400

61kD

816

Q13554

https://www.uniprot.org/uniprotkb/Q13554

Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (Probable).

Expressed in skeletal muscle.

Recombinant human CAMK2 between 1-503 amino acids.

Mouse

Monoclonal

IgG1

affinity purified by Protein G

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.