The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]

ABC 21;
ABC B4;
ABC21;
ABCB 4;
ATP binding cassette sub family B MDR/TAP member 4;
ATP binding cassette sub family B member 4;
ATP-binding cassette sub-family B member 4;
MDR 3;
MDR2;
MDR2/3;
MDR3;
MDR3 P glycoprotein;
MDR3 P gp;
MDR3_HUMAN;
Multidrug resistance protein 3;
Multiple drug resistance 3;
P glycoprotein 3;
P-glycoprotein 3;
PFIC 3;
PFIC3;
PGY 3;
PGY3.

Human

WB

WB 1:500-2000

142kD

5244

P21439

https://www.uniprot.org/uniprotkb/P21439

Cell membrane.

Highly expressed in brain, heart, kidney, stomach, testis and placenta.

Recombinant human ABCB4.

Mouse

Monoclonal

IgG1,k

affinity purified by Protein G

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.