This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]

B61;
ECKLG;
EFL 1;
EFL1;
EFNA 1;
EFNA1;
EFNA1_HUMAN;
EPH related receptor tyrosine kinase ligand 1;
EPH-related receptor tyrosine kinase ligand 1;
Ephrin-A1;
Ephrin-A1, secreted form;
EphrinA1;
EPLG 1;
EPLG1;
Immediate early response protein B61;
LERK 1;
LERK-1;
LERK1;
Ligand of eph related kinase 1;
OTTHUMP00000033242;
OTTHUMP00000033271;
secreted form;
TNF alpha-induced protein 4;
TNFAIP 4;
TNFAIP4;
Tumor necrosis factor alpha induced protein 4;
Tumor necrosis factor alpha-induced protein 4.

Human,Mouse,Rat

IHC,IF,ICC

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

19/22kD

1942

P21709

https://www.uniprot.org/uniprotkb/P21709

Cell membrane; Lipid-anchor, GPI-anchor.
Ephrin-A1, secreted form: Secreted.

Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level).

KLH conjugated synthetic peptide derived from human Ephrin A1

Rabbit

Polyclonal

IgG

affinity purified by Protein A

Liquid

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.